ADVANCES IN DRUG DESIGN AND FORMULATION 

BOOK DESCRIPTION:

Advances in Drug Design and Formulation presents a comprehensive and forward-looking exploration of modern pharmaceutical sciences, highlighting the rapid transformation of drug discovery and formulation driven by computational intelligence, material science, and innovative delivery technologies. This edited volume brings together contributions from academicians, researchers, and industry professionals, offering both theoretical foundations and practical insights into next-generation drug development. The book covers cutting-edge topics such as AI-driven structure-based de novo drug design, microencapsulation technologies, nanomedicine-enabled drug delivery systems, 3D printing in pharmaceutical formulations, herbal and transdermal drug delivery, drug repurposing strategies, and regulatory and translational challenges. Special emphasis is placed on the integration of artificial intelligence, molecular modeling, machine learning, and data-driven formulation platforms to improve drug efficacy, bioavailability, safety, and patient compliance. By bridging computational pharmaceutics with experimental and formulation sciences, this volume addresses key challenges faced during the translation of laboratory research into clinically viable therapies. Each chapter is carefully curated to reflect current trends, emerging paradigms, and future prospects in pharmaceutical research and development. Intended for postgraduate and doctoral students, researchers, academicians, formulation scientists, and pharmaceutical industry professionals, Advances in Drug Design and Formulation serves as a valuable reference work and an inspiring resource for interdisciplinary innovation in drug discovery and delivery. The inclusion of award-winning chapters further underscores the scientific rigor and academic excellence embodied in this publication. 

AUTHOR DESCRIPTION:

Sonali C. Kale Chapter: The Future of Drug and Formulation Innovation: AI-Driven Structure-Based De Novo Design Paradigms Sonali C. Kale is a researcher in the field of computational drug design and pharmaceutics, with a strong focus on structure-based drug discovery, artificial intelligence, and molecular modeling. Her work emphasizes the integration of machine learning, evolutionary algorithms, and modern formulation strategies to accelerate rational drug development.

Shruti Kandale Chapter: Beyond Boundaries: Microcapsules Transforming Modern Pharmaceutics Shruti Kandale is a pharmaceutical researcher specializing in novel drug delivery systems, particularly microencapsulation and controlled release technologies. Her research interests include formulation design, bioavailability enhancement, and cross-disciplinary applications of encapsulation in pharmaceuticals and allied industries.

Avdhut Anilkumar Talwar Chapter: Emerging Paradigms in Drug Design: A Review of Formulation Strategies Avdhut Anilkumar Talwar is engaged in pharmaceutical research with a focus on modern formulation approaches and emerging drug design strategies. His academic interests include improving drug performance through innovative excipients, delivery systems, and formulation optimization techniques.

Nihar Ranjan Sahoo Chapter: Translational and Regulatory Challenges in the Development of Nanomedicine-Enabled Drug Delivery Devices Nihar Ranjan Sahoo is a researcher in nanomedicine and pharmaceutical regulatory science. His work explores translational barriers, regulatory frameworks, and safety considerations associated with advanced nanotechnology-based drug delivery systems.

Sakshi Suresh Jagtap Chapter: Pharmacological Management of Hypertension: Current Therapies and Future Perspective Sakshi Suresh Jagtap is a researcher with interests in pharmacology and therapeutic management of cardiovascular disorders. Her work focuses on current antihypertensive therapies and emerging treatment strategies aimed at improving clinical outcomes.

Anuja Nirwane Chapter: Therapeutic Prospect of Punarnava Kwath: Anti-Inflammatory Activity by Egg Albumin Denaturation Technique Anuja Nirwane is a researcher in herbal and traditional medicine, with expertise in experimental pharmacology and natural product evaluation. Her work emphasizes scientific validation of herbal formulations for anti-inflammatory and therapeutic applications.

Tanuja Gaikwad Chapter: Artificial Intelligence in Medicines Development: Revolutionizing Drug Discovery and Clinical Trials Tanuja Gaikwad is actively involved in research on artificial intelligence applications in pharmaceutical sciences. Her academic interests include AI-assisted drug discovery, predictive modeling, and the optimization of clinical trial processes.

Ishwari A. Nimbalkar Chapter: Formulation and Evaluation of Herbal Chamomile Transdermal Patch for Anti-Acne and Antifungal Properties Ishwari A. Nimbalkar is a formulation scientist with expertise in herbal drug delivery and transdermal systems. Her research focuses on developing patient-friendly topical and transdermal formulations using natural therapeutic agents.

Ankita A. Patil Chapter: Advancements in 3D Printing for Transdermal and Topical Drug Delivery Ankita A. Patil is a researcher in advanced pharmaceutical manufacturing technologies. Her work centers on 3D printing applications in drug delivery, personalized medicine, and next-generation dosage form development. 

 Nikita G. Tuppekar is a pharmaceutical researcher specializing in drug repurposing, computational drug discovery, and translational research approaches. Her work focuses on integrating in silico techniques such as molecular docking, virtual screening, and bioinformatics with experimental validation studies to identify new therapeutic uses for existing drugs. She emphasizes accelerating drug development timelines through cost-effective and evidence-based repurposing strategies.